Patient Services and Support

PAH Pathways^®

One point of contact for every step of your journey
Living with pulmonary arterial hypertension (PAH) isn't easy. That's why Actelion offers comprehensive services and support programs through PAH Pathways for patients like you, who are on Tracleer. From getting started on Tracleer to education and support, these programs are here for you every step of the way.

If you're a patient who has been prescribed Tracleer, you'll enjoy several PAH Pathways benefits. PAH Pathways provides:

• Access to Tracleer—to make sure you get your medicine quickly
• Insurance information and financial assistance—to help find the answers you need and help pay for your medicine, if eligible
• Access to Sure Steps^™—to provide education and support for your PAH journey
• LabTrac^™—to help your healthcare team to track your lab results

If you have any questions, call PAH Pathways toll free at 1-866-ACTELION
(1-866-228-3546) Monday‑Friday, 9 am‑8 pm (ET) / 6 am‑5 pm (PT).

Access to treatment through the
Tracleer Access Program (T.A.P. ^®)

Because of the risk of liver damage and serious birth defects associated with Tracleer, you must be enrolled in T.A.P. to receive Tracleer.

PAH Pathways administers the T.A.P program and works with your healthcare team, insurance company, and specialty pharmacy to make sure you get your medicine quickly.

To start treatment with Tracleer, you must review essential safety information with your healthcare provider, complete a Tracleer Enrollment and Renewal form, and agree to have important monthly tests. Your first step is reviewing the Tracleer Medication Guide (found in the Patient Essentials Guide) with your healthcare provider. You must then go for pretreatment liver function and, if applicable, pregnancy tests. These tests rule out that you are pregnant or that you have liver problems before starting treatment with Tracleer. This is important because of the risk of liver damage and serious birth defects associated with Tracleer.

Here's how it all comes together:

1. Your healthcare provider prescribes Tracleer and you are enrolled in the Tracleer Access Program
   
   
2. PAH Pathways contacts you
   A reimbursement counselor will:
   • Follow up with your enrollment in T.A.P.
   • Answer questions you have about insurance coverage or costs for Tracleer
   • Provide information on financial assistance programs, if needed
   
   You can call PAH Pathways with questions. It's important to call
   PAH Pathways if:
   • A reimbursement counselor leaves you a message
   • You lose your insurance or your insurance changes
   
   
3. Tracleer is delivered to you:
   • Tracleer is not available in your retail pharmacy; rather it is carried by a network of specialty pharmacies certified by Actelion to dispense Tracleer. Your specialty pharmacy ships Tracleer directly and conveniently to your home or healthcare provider's office each month you are on treatment.
   • Because of the risks associated with Tracleer, you must have liver function and pregnancy tests each month. Your specialty pharmacy will call you regularly to confirm that you have had your liver function tests and (if applicable) pregnancy tests each month before they ship your medication.
   • If you don't confirm with your specialty pharmacy that you have had your tests or if you become pregnant, your specialty pharmacy will not be able to ship Tracleer to you and will contact your healthcare provider.
   • You will receive a Medication Guide with each shipment and you should read it monthly because there may be new information.
   
   
4. Your healthcare provider renews your Tracleer enrollment every year. To continue on Tracleer, you must renew your T.A.P. enrollment each year by again reviewing the Medication Guide and completing the Tracleer Enrollment and Renewal form with your healthcare provider.

Insurance information and financial assistance

Additional help from PAH Pathways is just a phone call away. PAH Pathways Counselors can help you find the answers you need. They can help simplify and explain insurance coverage and financial assistance by:

• Verifying your insurance coverage
• Clarifying your co-payment amount before your prescription is filled
• Assisting with claims appeals and grievances
• Offering information about potential financial assistance to help you pay for medicine if you are eligible
• Assisting with Medicare/Medicaid issues, including program enrollment and drug assistance

To learn more about insurance coverage and financial assistance, call a PAH Pathways Counselor at 1‑866‑ACTELION (1-866-228-3546) or visit PAHPathways.com.

The Caring Voice Coalition (CVC) is another resource. CVC is an independent third party who offers support programs for patients with chronic illness that include financial assistance, insurance education and counseling.

Access to Sure Steps

Sure Steps is an education and support program brought to you by PAH Pathways. It's designed to answer your questions and help you make the most of your Tracleer treatment. When you become a member of Sure Steps, you gain ongoing access to patient education materials and one‑on‑one phone support from a team of Nurse Counselors to answer your questions about PAH and Tracleer. All at no cost to you.


Enroll in Sure Steps today!
Or simply call 1-866-ACTELION (1-866-228-3546)
Monday — Friday, 8 am - 11 pm (ET) for assistance in English or
1-877-783-7791 Monday — Friday, 9 am - 5 pm (ET) for assistance in Spanish.

LabTrac^™

Your healthcare provider may be participating in LabTrac, a program that makes it easier for your healthcare team to track your lab results, and it is available to you at no cost.

IMPORTANT SAFETY INFORMATION
Because of the risks associated with Tracleer, this medication may be prescribed by your doctor only through the Tracleer Access Program.

Liver damage: Tracleer can cause serious liver damage, including in rare cases liver failure and, in situations with regular liver testing, unexplained liver cirrhosis. So you must have a blood test to check your liver function before you start Tracleer and each month after that. Call your doctor right away if you have any of these symptoms of liver problems: nausea, vomiting, fever, unusual tiredness, abdominal (stomach area) pain, or yellowing of the skin or the whites of your eyes (jaundice).

Serious birth defects: Tracleer is very likely to cause serious birth defects. It is important not to be or to become pregnant while taking Tracleer or one month after stopping treatment and to have a pregnancy test before you start the drug and each month thereafter. It is very important for you to use reliable forms of birth control while taking Tracleer. Hormonal contraceptives should not be used alone because they may not be effective in patients taking Tracleer.

Do not take Tracleer with glyburide because it may increase your chance of liver injury. Do not take Tracleer with cyclosporine-A because it may increase your chance of side effects.

Please see Additional Safety Information.
Please see full Prescribing Information, including BOXED WARNING and Medication Guide.

Learn more about the benefits of Sure Steps and how you can enroll