Sure Steps^™

Helping you every step of the way

Sure Steps is an education and support program for Tracleer patients and caregivers designed to answer your questions about Tracleer and PAH, and help you make the most of your treatment. When you enroll in Sure Steps, you'll receive—at no cost to you—information to help you better manage your PAH.

Becoming a member of Sure Steps gives you access to information and the ability to connect with other PAH patients.

• Educational Materials
• One-on-one phone support
• Sure Steps website
• Sure Steps Connect^™
• Caregivers can take part in Sure Steps too!

Educational Materials

Information-packed communications designed to help keep you informed and on track with your treatment. Includes:

• Educational mailings to help you better understand PAH and your treatment with Tracleer (for WHO Class II, III and IV)
• Personal support items such as journals and calendars to record your progress and help you remember key dates

One-on-one phone support

Sure Steps Nurse Counselors are trained nurses you can call for help finding answers to questions about important topics such as:

• What to expect from your treatment with Tracleer
• Why monthly liver function and pregnancy testing is so important
• Healthy living tips
• Why following your healthcare provider's instructions is so important
• How Sure Steps can help you and your caregiver

Get ongoing information and support at no cost to you. Sign up for Sure Steps today!

Sure Steps Connect

Sure Steps Connect is a PAH conference series that you can watch online. These educational conferences allow patients and caregivers to watch experts discuss a variety of PAH- and Tracleer-related topics. At the end of each of these live events, the speakers will take time to answer your questions. Visit www.SureStepsConnect.com to learn more.

Caregivers can take part in Sure Steps too!

At Sure Steps, we recognize the importance of caregivers and encourage them to participate.

They can:

• Get involved by speaking directly with Sure Steps Nurse Counselors
• Participate on the Sure Steps website
• Participate in Sure Steps Connect-where they can see and talk with PAH experts

IMPORTANT SAFETY INFORMATION
Because of the risks associated with Tracleer, this medication may be prescribed by your doctor only through the Tracleer Access Program.

Liver damage: Tracleer can cause serious liver damage, including in rare cases liver failure and, in situations with regular liver testing, unexplained liver cirrhosis. So you must have a blood test to check your liver function before you start Tracleer and each month after that. Call your doctor right away if you have any of these symptoms of liver problems: nausea, vomiting, fever, unusual tiredness, abdominal (stomach area) pain, or yellowing of the skin or the whites of your eyes (jaundice).

Serious birth defects: Tracleer is very likely to cause serious birth defects. It is important not to be or to become pregnant while taking Tracleer or one month after stopping treatment and to have a pregnancy test before you start the drug and each month thereafter. It is very important for you to use reliable forms of birth control while taking Tracleer. Hormonal contraceptives should not be used alone because they may not be effective in patients taking Tracleer.

Do not take Tracleer with glyburide because it may increase your chance of liver injury. Do not take Tracleer with cyclosporine-A because it may increase your chance of side effects.

Please see Additional Safety Information.
Please see full Prescribing Information, including BOXED WARNING and Medication Guide.